Getting a Structure from Multiple Tomograms of HIV Capsids
The aim of this exercise is to get familiar with managing multiple tomograms through the Dynamo catalogue and to develop good strategies for alignment projects to reach a reasonable structure from a set of tomograms. This is an exercise and not a tutorial or walkthrough. Therefore only a few hints on how to proceed are given. The idea is that you come up with your own solutions by applying the knowledge that you acquired during the workshop to a more realistic case. It is recommended to get familiar with at the advanced starters guide and the lattice walkthrough before starting this exercise.
We prepared a set of 6 tomograms, each containing one VLP. (empiar id, paper)
Reach a resolution at around 10 angstrom, i.e., alpha helices should start to be visible in the final average. Hexamer.
Based on lattice walkthrough. Parameters. Use GPU on sciCORE.